Urinary Placental Growth Factor in Pregnancies Complicated by Preeclampsia
ثبت نشده
چکیده
منابع مشابه
Placental expression of VEGF family mRNA in adverse pregnancy outcomes.
INTRODUCTION The pregnancy complications preeclampsia, gestational hypertension, small for gestational age infants (SGA) and pre-term birth (PTB) affect approximately 21% of all pregnancies. The Vascular Endothelial Growth Factor family (VEGF) is implicated in the pathogenesis of these complications. We aimed to evaluate the placental mRNA expression of VEGFA, PGF, FLT1 and KDR in pregnancies c...
متن کاملIn preeclampsia, the placenta grows slowly along its minor axis.
A small placental surface area at birth is associated with an increased risk of hypertension in the offspring in later life. Preeclampsia is associated with impaired implantation and with increased blood pressure in the offspring. We hypothesized that preeclampsia would be associated with a small placental surface area. We studied placental size in 6410 deliveries at the Helsinki University Cen...
متن کاملLoss of Thrombomodulin in Placental Dysfunction in Preeclampsia.
OBJECTIVE Preeclampsia is a pregnancy-specific syndrome characterized by placental dysfunction and an angiogenic imbalance. Systemically, levels of thrombomodulin, an endothelium- and syncytiotrophoblast-bound protein that regulates coagulation, inflammation, apoptosis, and tissue remodeling, are increased. We aimed to investigate placental thrombomodulin dysregulation and consequent downstream...
متن کاملExpression of nuclear factor-kappa B and placental apoptosis in pregnancies complicated with intrauterine growth restriction and preeclampsia: an immunohistochemical study.
Preeclampsia affects 7-10% of all pregnancies, and is a major cause of maternal and fetal morbidity and mortality. Although enhanced apoptosis is well known in placentas with preeclampsia, the role of transcription factor nuclear factor-kappa B (NF-kappa B) in the process is still being debated. In this work, we investigate the relationship between NF-kappa B expression and trophoblastic cell a...
متن کاملA Lipidomic Analysis of Placenta in Preeclampsia: Evidence for Lipid Storage
In preeclampsia, maternal insulin resistance leads to defective expansion of adipocytes, enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis, maternal hypertriglyceridaemia and the potential for ectopic fat storage. Our aim was to quantitate and compare the total amount and type of lipid in placenta from pregnancies complicated with preeclampsia and healthy pre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012